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Profile for Daniel Summer Gareau

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dan@dangareau.net

The skin is an organ that represents an exquisite feat of bioengineering. The skin surface provides an easily accessible imaging target that contains the vascular system, the gland system, the nervous system and hair bulbs, with rapidly multiplying stem cells that proliferate to replenish the epidermis. We must keep ourselves from the outside world with this organ and remain free of disease. Therefore, elucidating microscopic physiology must be achieved through imaging in order to understand the system or assess and treat any skin disease. The morphological nature of cellular processes in the dynamic setting of the skin requires the synthesis of optical engineering fundamentals with clinical research. My research is focused on building the tools to image the skin system. The ultimate goal is to treat disease armed with biological understanding gained by technology-enabled vision. I hope to enable detection of cancer earlier and more completely. At the end of this pursuit is the beginning of cancer.

Daniel's home page

http://www.dangareau.net

Selected publications

6. Gareau D.S., Li Y., Huang B., Eastman Z., Nehal K.S., Rajadhyaksha M., Confocal mosaicing microscopy in Mohs skin excisions: feasibility of rapid surgical pathology, Journal of Biomedical Optics, 13(5):054001, 2008.
1. Gareau D.S., Bargo P.R., Horton W.A., Jacques S.L., Confocal fluorescence spectroscopy of subcutaneous cartilage expressing green fluorescent protein versus cutaneous collagen autofluorescence, Journal of Biomedical Optics, 9:254-258, 2004
2. Gareau D.S., Merlino G., Corless C., Kulesz-Martin M., Jacques S.L., Noninvasive imaging of melanoma with reflectance mode confocal scanning laser microscopy in a murine model, Journal of Investigative Dermatology 127:2184-2190, 2007.
3. Patel Y., Gareau D., Nehal K., Rajadhyaksha M., Multimodal confocal mosaicing of basal cell carcinomas in Mohs surgical skin excisions, Journal of the American Academy of Dermatology, 56(2):AB2, 2007.
4. Pan Y., Gareau D.S., Scope A., Rajadhyaksha M., Mulani A., Marghoob A., Polarized and nonpolarized dermoscopy, Archives of Dermatology, 44(6):828-829, 2008
5. Nehal K., Gareau D., Rajadhyaksha M., Skin Imaging With Reflectance Confocal Microscopy Seminars in Cutaneous Medicine and Surgery, 27:37-43, 2008.
7. Gareau D.S., Patel Y.G., Li Y., Aranda I., Halpern A.C., Nehal K.S., Rajadhyaksha M., Confocal mosaicing microscopy in skin excisions: a demonstration of rapid surgical pathology, Journal of Microscopy, 233(1):149-159, 2009.
8. Gareau D.S., Karen J.K., Dusza S.W., Tudisco M., Nehal K.S., Rajadhyaksha M., Sensitivity and specificity for detecting basal cell carcinomas in Mohs excisions with confocal fluorescence mosaicing microscopy, Journal of Biomedical Optics, Volume 14, no. 3, 2009.
9. Karen J.K., Gareau D.S., Dusza S.W., Tudisco M., Rajadhyaksha M., Nehal K.S., Detection of basal cell carcinomas in Mohs excisions with fluorescence confocal mosaicing microscopy, British Journal of Dermatology, 160(6):1242-1250, 2009.
10. Gareau D. S., The feasibility of digitally stained multimodal confocal mosaics to simulate histopathology, Journal of Biomedical Optics, Volume 14, no. 3, 2009.

This personal profile was last updated about 1 year ago



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